Dr. Andrew Huberman – Peptides, Functions, and Mechanisms (#876)

Andrew Huberman, Ph.D.neurologist and tenured professor in the Department of Neurobiology and Ophthalmology at Stanford University School of Medicine, where he runs the Huberman Lab. His research includes brain development, visual perception and the correction of blindness, the neuroscience of stress and resilience, and neural plasticity. He has published more than 75 peer-reviewed articles in top journals including The environment, Science, Cellagain Neuronand his honors include the Cogan Award, the McKnight Neuroscience Scholar Award, and the Pew Biomedical Scholar Award.

In 2021, he launched the Huberman Lab podcast, which became and remains the most popular health and science podcast in the world. Dr. Huberman is the founder of Scicomm Media, a podcasting company Huberman Lab, Do with Dr. Andy Galpinagain David Senra.
He is the author of Protocols: A Workbook of the Human Body.

Please enjoy!

This episode was brought to you by:

• Helix Sleep premium mattresses
• ProLon supports the science of a Fasting Mimicking Diet that helps stimulate cellular regeneration by fasting, while eating a nutritious diet.
• Eight Sleep Pod 5 cover sleeping solution for flexible cooling and heating
• Important high quality creatine for mental and muscle support

Please enjoy!

ListenSpotify

ListenApple Podcasts

ListenTo cover us

More podcast platforms

Listen to this episode on Apple Podcasts, Spotify, Overcast, Podcast Addict, Pocket Casts, Castbox, YouTube Music, Amazon Music, Audible, or your favorite podcast platform.

Transcript

• This episode (coming soon)
• All episodes

Show Notes

Connect with Dr. Andrew Huberman

Website | The Huberman Lab Podcast | Twitter | YouTube | Instagram

Previous Appearance of Dr. Andrew Huberman on the Tim Ferriss Show

• Dr. Andrew Huberman – Basics of Physical and Mental Health, Top Supplements, Sexual and Reproductive Health, Sleep Preparation, Psychedelics, and More | The Tim Ferriss Show #660
• Dr. Andrew Huberman – Neurobiologist for Improving Sleep, Improving Performance, Reducing Anxiety, Increasing Testosterone, and Using the Body to Control the Mind | The Tim Ferriss Show #521

Movies, Shows, and Books

• Protocols: A Workbook of the Human Body by Andrew D. Huberman, Ph.D. | Amazon
• Bad Science: Quacks, Hacks, and Big Pharma Flacks by Ben Goldacre | Amazon
• Bigger, Stronger, Faster* | Main Video
• The Dark Witch | Main Video
• The Eden Project: In Search of the Extraordinary by James Hollis | Amazon
• The 4-Hour Body: The Unexpected Guide to Fast Fat Loss, Amazing Sex, and Being Superhuman by Tim Ferriss | Amazon
• Principles of Neuroscience by Eric R. Kandel, John D. Koester, Sarah H. Mack, and Steven A. Siegelbaum | Amazon
• Ride the Giants | Main Video
• Under Saturn’s Shadow: Wounding and Healing in Men by James Hollis | Amazon

People

• Canelo Alvarez
• Marc Andreessen
• Abu Bakr
• Martha Beck
• Chris Bell
• Mark Bell
• Hafthór “Thor” Björnsson
• Helen Blau
• Robin Carhart-Harris
• Jeff Cavaliere
• Edward Chang
• Ed Coan
• Paul Conti
• Gül Dölen
• Jonathan Downer
• Dan Gable
• Ben Goldacre
• Jennifer Groh
• Laird Hamilton
• James Hollis
• Alex Honnold
• Shelby Houlihan
• James Schwartz
• Thomas Jessell
• Arthur Jones
• Eric Kandel
• James Magnussen
• Christopher McCurdy
• Mike Mentzer
• Rob Mohr
• Ozzy Osbourne
• Ivan Pavlov
• Dean Potter
• Rick Rubin
• Brad Schoenfeld
• James Schwartz
• Arnold Schwarzenegger
• Andy Stumpf
• Casey Viator
• Matthew Walker
• Nolan Williams
• Dorian Yates

Training with Dorian Yates

• American College of Sports Medicine Ranking. Medicines for Resistance Training and Muscle Activity, Hypertrophy, and Physical Performance in Healthy Adults: An Overview of Reviews | Medicine and Science in Sports and Exercise
• Dorian Yates on Super Strength Training, Injury Prevention, and Building Superior Muscle | The Tim Ferriss Show #235
• Dose-Response Relationship Between Weekly Resistance Training Volume and Increase in Muscle Mass: A Systematic Review and Meta-Analysis | Journal of Sports Science
• Effects of Low- vs. High-Load Resistance to Muscle Strength and Hypertrophy in Well-Trained Men | Journal of Strength and Conditioning Research
• Effects of Repeated Resistance Training to Failure or Failure on Muscle Strength and Hypertrophy: A Systematic Review and Meta-Analysis | Journal of Sports and Health Sciences
• How Many Times Per Week Should Muscles Be Trained To Increase Muscle Hypertrophy? A Systematic Review and Meta-Analysis of Studies Examining the Effects of Frequency of Resistance Training | Journal of Sports Science
• Strength and Hypertrophy Changes Between Low- vs. High-Load Resistance Training: A Systematic Review and Meta-Analysis | Journal of Strength and Conditioning Research

Facilities and Procedures

• American Made Energy Resource | Rogue Fitness
• AssaultBike Classic | Suitability of Attacks
• Custom Strength and Exercise Equipment | Sorinex
• Hammer Strength Plate-Loaded Four Way Neck | Fitness for Life
• Jeff Cavaliere: Build Muscle, Great Posture & Injury Resistance | Huberman Lab
• Pit Shark Belt Squat | Rogue Fitness
• Schwinn AirDyne AD7 | Schwinn Fitness
• Science-Based Performance and Supplements | ATHLEAN-X

Psychedelics, Depression, and Neuroplasticity

• Transcend Therapeutics Discovery | Cleanser
• Positive Effects of MDMA Co-Administration on Psilocybin Response in Healthy Subjects | ClinicalTrials.gov
• Midomafetamine/MDMA Complete Answer Book | The FDA
• Guide to Psychedelic-Drug Clinical Investigation | The FDA
• MAPP2, a Phase 3 Trial of MDMA-Assisted Therapy for PTSD | MAPS
• MDMA-Assisted Therapy for Moderate to Severe PTSD: A Randomized, Placebo-Controlled Phase 3 Trial | Natural Medicine
• Psilocybin and MDMA for PTSD | ClinicalTrials.gov
• Psychedelics Reopens Key Learning Period for Social Reward | The environment

Accelerated TMS and D-cycloserine

• A Randomized, Double-Blind, Controlled Comparison of NRX-101 vs. Placebo for Adults Treated with Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial | ClinicalTrials.gov
• Efficacy of Adjunctive D-Cycloserine to Intermittent Theta-Burst Stimulation for Major Depressive Disorder: A Randomized Clinical Trial | JAMA Psychiatry
• Experimental Depression Treatment About 80% Effective in Controlled Studies | Stanford Medicine
• Neuroplasticity-Enhanced TMS Therapy | Ampa Health
• One day Tms medication with Pharmacological Augmentation of Plasticity: Five cases | Transcranial Magnetic Stimulation

Cortisol Timing, Light, Exercise, and Sleep

• The Circadian System Modulates the Cortisol Awakening Response in Humans | Frontiers in Neuroscience
• Effects of Post-Awakening Light Exposure on Cortisol-Induced Responses in Healthy Males | Psychoneuroendocrinology
• Light Affects Morning Salivary Cortisol in Humans | Journal of Clinical Endocrinology & Metabolism
• Transitioning from Dim to Bright Light in the Morning Induces Elevated Cortisol Levels | Journal of Clinical Endocrinology & Metabolism

Peptides and Metabolic Drugs

• Certain Substances in Bulk Drugs to be Used in Compounding That May Present Significant Safety Hazards | US Food and Drug Administration
• Consolidation and the FDA: Questions and Answers | US Food and Drug Administration
• Effects of Retatrutide on Body Composition in People With Type 2 Diabetes: A Phase 2, Double-Blind, Parallel-Group, Placebo-Controlled, Randomized Trial | Lancet Diabetes & Endocrinology
• Egrifta (Injectable Tesamorelin) Prescribing Information | US Food and Drug Administration
• FDA BPC-157 Briefing Document (2026) | US Food and Drug Administration
• FDA Concerns About Unapproved GLP-1 Drugs Used for Weight Loss | US Food and Drug Administration, including retatrutide
• Mounjaro (Tirzepatide) Prescribing Information | US Food and Drug Administration
• Safety of Intravenous Administration of BPC157 in Humans: A Pilot Study | Alternative Therapies in Health and Medicine
• Banned List 2026 | World Anti-Doping Agency
• Vyleesi (Bremelanotide Injection) Prescribing Information | US Food and Drug Administration
• What You Should Know About Retatrutide | Eli Lilly and Company, and Phase 3 Update: Lilly’s Triple Agonist, Retatrutide, Delivered Strong Weight Loss in Pivotal Phase 3 Obesity Trial | Eli Lilly and Company

Sleep, DORAs, Meditation, and Vestibular stimulation

• How to Comfort and Encourage Sleep in Crying Babies Using Transport Feedback | Current Biology
• Effects of Climate on Sleep and Circadian Rhythm | Journal of Physiological Anthropology
• Neurofluid Circulation Changes During Focused Attention Style Meditation | Proceedings of the National Academy of Sciences
• Quviviq (Daridorexant) Prescribing Information | US Food and Drug Administration
• Smart Ring for Sleep and Health | Oura
• Suvorexant Significantly Reduces Tau Phosphorylation and A? in the Human CNS | Annals of Neurology
• Open Human Performance & Healthspan | WHOOP
• Whole-Night Continuous Rocking Features Automatic Mood Adjustments and Sleep and Memory Benefits | Current Biology

Regenerative Medicine, Cartilage, and Kratom Research

• Important Patient and Consumer Information on Regenerative Medicine | US Food and Drug Administration
• Blocking a Master Regulator of Aging Regenerates Joint Cartilage in Mice | Stanford Medicine
• Kratom Resources | University of Florida College of Pharmacy

Long Light, Outdoor Time, and Multilingualism

• Multilingualism Protects Against Accelerated Aging in a Cross-Sectional and Longitudinal Analysis of 27 European Countries | Natural Aging
• Photobiomodulation-Underlying Mechanism and Clinical Applications | Journal of Clinical Medicine
• The Protective Effect of Bilingualism on Aging, MCI, and Dementia: A Community-Based Study | Alzheimer’s & Dementia
• Review of light parameters and photobiomodulation performance: Jump to the Challenge | Journal of Biomedical Optics
• Time Spent in Outdoor Activities in Relation to the Prevention and Control of Myopia: A Meta-Analysis and Systematic Review | Acta Ophthalmological

Enhanced Games and Anti-Drug Crimes

• Olympic Hopeful Blames Burrito For His Positive Drug Test | NPR
• Athletics: Modafinil Is Drug of Choice, Says IAAF Official | The Independent
• Australian swimmer James Magnussen Says He’ll ‘Gain Juice to the Gills’ to Win $1.5m Prize in Advanced Sports | The guard
• Gkolomeev Claims $1M Bonus for 50 Meters Freestyle at Advanced Games | Reuters
• Advanced Sports Competition | Advanced Games
• Blacklist | World Anti-Doping Agency
• Awarded to CAS in Shelby Houlihan Nandrolone Case | Court of Arbitration for Sport

Posted by Dr. Andrew Huberman – Peptides, Functions, and Mechanisms (#876) appeared first on Author Tim Ferriss’ Blog.